Entries by visicort_admin

New study reveals how short-lived mesenchymal stem cells re-programme the immune system to prevent corneal transplant rejection

The laboratory of VISICORT researcher Prof. Thomas Ritter has demonstrated that intravenous infusion of mesenchymal stem cells (MSCs) can reduce the rate of rejection of experimental corneal transplants (Treacy et al., Am J Transplant. 2014 Sep;14(9):2023-36) and we are now actively working toward performing a clinical trial of MSCs in human corneal transplant recipients at […]

Report on EU MSC2 2015 meeting – Shaping the future of MSC Therapy

ADIPOA-2 researchers participated in the EU-MSC2 meeting in Leiden on the 7th and 8th of September 2015 The two-day meeting brought together researchers from nine EU-funded projects pursuing MSC research. In addition to REDDSTAR, other projects represented at the meeting included ADIPOA-2, REDDSTAR, Stellar, RETHRIM, REACH, MERLIN,SCIENCE and NEPHSTROM. After a welcome from Henri Lenferink, Mayor of Leiden, European […]

VISICORT consortium mets at the Aarhus University Hospital

The VISICORT consortium met at the Aarhus University Hospital, Aarhus, Denmark on the 12–13 November for the project’s third plenary meeting. Teams of researchers from each of the twelve partners involved in the project listened to reports of the work being carried out in each of the project’s workpackages. These included reports of the preclinical […]

Winning essay writers visit REMEDI

The Regenerative Medicine Institute (REMEDI) at NUI Galway was delighted to host a visit by winning essay writers from St Nathy’s College,  Ballaghdereen, Co. Roscommon. Each of the winning students had written an essay on the topic of stem cell, outlining the history of their discovery, and their potential to revolutionise the treatment of a […]

Italian Study of Corneal Transplantation  (Y. O’Donoghue, Orbsen Therapeutics)

A recently published study in Transplantation Proceedings presents changing trends in corneal transplantation (CT) from Italy.  The Corneal Transplant Epidemiological Study (CORTES) presents seven years of data, 2002 to 2008, from a prospective study which included over 13,000 CT.  In general, trends were driven by changing clinical practise and mirrored similar trends observed in Western […]

Systemic immunosuppression may improve long-term graft survival in corneal transplants at high risk of rejection

A recent study from one of the five clinical sites for VISICORT, Bristol Eye Hospital, reports that systemic immunosuppression appears to improve long-term graft survival in corneal transplants at high risk of rejection.1 Lead author of the study, Dr Sing-Pey Chow, reports: Immunological graft rejection remains the leading cause of graft failure in corneal transplantation. […]

New data from UK Transplant Registry shows similar 2-year rejection rates for full thickness and endothelial corneal transplants in first-time recipients

New data from UK Transplant Registry shows similar 2-year rejection rates for full thickness and endothelial corneal transplants in first-time recipients Corneal transplantation involves the replacement of damaged cornea with donor tissue. For some of the commonest forms of corneal disease, there are currently two primary approaches to transplantation: Full-thickness, or penetrating keratoplasty (PK), which […]

VISICORT partners involved in exciting new stem cell project

VISICORT partners NUI Galway, Orbsen, and Pintail are involved in NEPHSTROM, a new European project, which was launched last week. NEPHSTROM involves eleven partners from Ireland, the UK, Germany, and the Netherlands, and has received €6 million funding under the European Union’s Horizon 2020 funding programme. NEPHSTROM will evaluate the clinical safety and efficacy of […]