Italian Study of Corneal Transplantation  (Y. O’Donoghue, Orbsen Therapeutics)

A recently published study in Transplantation Proceedings presents changing trends in corneal transplantation (CT) from Italy.  The Corneal Transplant Epidemiological Study (CORTES) presents seven years of data, 2002 to 2008, from a prospective study which included over 13,000 CT.  In general, trends were driven by changing clinical practise and mirrored similar trends observed in Western countries over the same period.   The study demonstrated the marked transformation in surgical approach to CT from Penetrating Keratoplasty to Endothelial Keratoplasty in recent years.  Of particular relevance to VISICORT is the 20% increase observed in re-grafts over the period; regraft was the second highest indication for corneal transplant over the study period.  Regrafts are considered as high-risk transplants and VISICORT’s immunomodulatory stem cell therapy aims to provide novel treatment for high-risk transplant recipients.